Jacketed Glass Reactor for Stirring, Homogenization, Crushing
| Equipment |
Item |
Reqirements and manufacturers |
vessel |
Fermenter body |
The size of fermenter takes in general use type as basis and The main material of the fermenter is made by 316Lstainless steel. The design pressure: P(inside)= 0.3Mpa, P(interlayer)= 0.3Mpa, The polishing precision: Ra0.4~0.6, the ratio between diameter and height: 1:2.5;
Total volume 10L
Working volume:30-75% |
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Sterilization method |
Auto sterilizing in situ (SIP) |
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Stirring system |
magnetic coupling stirring system at the top of the fermenter;; high-powered stirring oar, antifoam oar;; high-powered stirring oar, antifoam oar; AC electrical machine(TECO): infinite speed variation; rpm: 50~800rpm±1%,The height of the stirring oar can be adjusted, too. |
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Temperature detection and control |
Heat by thermostatic water tank and circulate by circulating pump(Grundfos, Denmark), autocontrol (cooling water+5ºC)~70ºC±0.1ºC,temperature probe(imported) |
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pH detection and control |
2.00-12.00±0.05pH, autocontrol by adding acid and base, pH sensor (Hamilton, Switzerland) and shielding lead (Switzerland). |
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DO detection and control |
0-150±3% displaying precision 0.1%, sensor ( Switzerland) and shielding lead(Hamilton, Switzerland) |
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Feed control |
uses peristaltic pump to add meterials |
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Antifoam control |
Tested by sencor and added antifoamer by peristaltic pump |
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Aeration detection and control |
Automatically control ventilatory capacity, the precision of nhaler : 0.01μ, displayed by rotameter a.
The range of flow adjusting of 20L germ fermenter :0~15L/min |
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pressure detection and control |
Automaticallycontrol exhaust by diaphragm cell valve ,and displayed by pressure gauge. |
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Pipeline and valve |
The pipelines and valves which are in contact with the zymotic fluid are made by 316L stainless steel, the valves are diaphragm cell valves |
| Control system |
BLBIO S Control System: on-site controller, the next crew for the Siemens S7-200 series PLC control system, it is a mature, stable, universal type of PLC, to suit a variety of automation applications, especially in manufacturing process control Application. Its modular, easy to implement distributed configuration and easy to master and so on, Siemens PLC control center has become a biological reaction process control implementation is economical and advanced control system, the system uses the touch screen display, on-site direct operations (menu type), all English menu and interface; also with the host computer for data transmission, data sampling and display tank, the system view of data analysis, reading settings.
10-inch LCD touch-sensitive screen as the display screen to display complete content-rich, user-friendly screen is simple, easy to operate. And disturbing each other. The control system can adapt to different range of sensors and actuators the output of the input signal with the signal anti-jamming system.
Software: Siemens S7+ FORCE CONTORL
Data collection and control module: Siemens S200 PLC controller and data collection and control module
1. Control |
Details For Product:
Safety Instruction
In order to safely use the glass reactor, please read the instruction carefully before using the instrument.
The supply voltage must be consistent with the provisions of this instrument.
- Please keep the electrical parts dry.
- The equipment used for the jacket layer should be on a plane with reactor, because the pressure caused by the high and low drop can easily make the reactor burst.
- Carefully clean and check the glass parts of the instrument before use, whether there is damage, interface installation is consistent.
- If there is solid material in use, do not put into large solid, crushed and then put into the kettle.
- Do not tighten the interface too tight, Loosen the connector regularly to avoid long - term locking.
- No load should not run at high speed.
- When loading the reaction medium, it is recommended not to exceed 2/3 of the liquid level of the reactor body.
- For explosive reactants, such as peroxides, azides, diazo compounds, etc. Be careful when using.
- For the reaction of gas generated by heating, Be careful not to form a closed system in the reactor.
- In the case of valuable solution, the simulation test should be done first, and the equipment can be used in normal operation when the equipment can meet the process and safety requirements.
- The solvent should be cleaned, vacuum dried, and soft cloth to wipe all kinds of oil stains, solvent residues left on the surface of the machine, keep clean.
- Clean the seal gasketes regularly. The method is to remove the sealing ring, check whether there is dirt on the shaft, wipe it with soft cloth, then apply a little vacuum grease, reinstall it, and keep the shaft and sealing ring smooth.
Introduction
The general understanding of the reactor is that the container with physical or chemical reaction, through the structural design and parameter configuration of the container, the heating, evaporation, cooling and low-speed mixing functions required by the process are realized.
The working principle of the reactor is that the reaction solvent can be stirred in the inner layer, and the interlayer can be heated or cooled by different cold and heat sources (freezing liquid, hot water or hot oil) for cycle heating or cooling reaction.
The materials in the reactor are heated or cooled by injecting constant temperature (high temperature or low temperature) hot solution media or cooling media. At the same time, stirring reaction can be carried out under normal pressure or negative pressure according to the requirements of use. After the reaction, the material can be released from the outlet of the bottom of the reactor, and the operation is extremely convenient.
Reactor is widely used in petroleum, chemical industry, rubber, pesticide, dye, medicine, food, used to complete vulcanization, nitrification, hydrogenation, alkylation, polymerization, condensation and other processes of pressure vessels, such as reactor, reaction pot, decomposition pot, polymerization kettle;
Feature
- high borosilicate glass has good chemical-physical attribute.
- Low speed booster motor; High torque; no spark; frequency control, smooth operation.
- PTFE rotary seal assembly; Patented product; High vacuum degree and long useful life.
- PTFE discharge valve, discharge completely, no leak/pollution to the solvent.
- PTFE stirring paddle, suitable for low and high viscosity liquid stirring and mixing.
- Selection of our company's heating and cooling circulating device, we match standard
connector and the suitable connection pipe.
Installation and Commissioning
1. Open the packing case, and check all components according the packing list.
2. First install stainless steel frame and make sure the brakes are closed.
3. Fixed main pole and condenser supporting rod, and all connection rods.
4. Install the motor and speed controller.
5. Mixing sealing components installed on the reactor cover and mount a stirring rod. The reactor cover buckled on the jacket vessel and screw seal. (When you install the lid, sealed surface coated with a small amount of vacuum grease, can be effective in reducing neck wear, and improve the vacuum degree).
6. All glass components are installed. (Put Vaseline or vacuum grease on the seal joint).
7. Installing the discharge valve.
8. Checking all the installation steps once more follow the drawing or picture .
Power on and test machine.
Jiangsu's KINGBEN Machinery Co., Ltd. is located in Dingyan Industrial Park, High-tech-Zone, Yancheng City, Jiangsu Province, china. It is a professional pharmaceutical equipment factory that integrates design, research and development, technical consulting, production, engineering installation, operation training, and after-sales service.
My product is used in various industrial fields such as biopharmaceuticals, lithium batteries, fine chemicals, cosmetics, powder metallurgy, food and beverage, new energy, and new materials. Various non-standard automation specialized equipment can be customized according to your needs.
For more than 20 years, my company has adhered to its unique technological advantages and upheld the principle of "quality first, unlimited innovation". My company has continuously launched high-quality products with "high standards" and has multiple innovative technologies in the field of softgel capsule production line, serving customers in over 30 countries and regions.
Cleaning method
1.the PTFE valve and connect joint needn't too tight and after test, remember to loose, prevent deformation.
2.disinfection is a part of the method chosen by the factory. Generally, it is necessary to simply spray it first and wipe it with a rag.
3.cleaning can be directly washed 3-4 times with distilled water when the reactor is in operation. If need deeply cleaned, can be washed with boiled water.
4.low concentration sodium hypochlorite solution cleaning.
The above methods are customers' feedback to us. The cleaning method is only for their production materials, and the specific method of cleaning the reaction kettle can be selected according to your own production materials.
After-Sale Service
1. This machine under normal conditions, due to manufacturing quality, our company is responsible for maintenance within 12 months from the date of shipment. Because of improper use to damage, the company takes repair costs according to practical condition.
Glass parts and Sealing rings are easy to broke, they are not in the warranty.
The Final explanation right belongs to the company.
Application and Maintenance
- Checking the power supply voltage, and make sure it is consistent with your country.
- Plug in, open the power switch on the frequency converter, to adjust speed.
- If the flow of material and the motor speed resonance, can change the motor speed to avoid it.
- Pay attention to the stirrer bar whether normal rotation.
- When circulating the hot oil, firstly should open the circulating switch.
- If sealing performance has reduce, pls check the sealing part that inside of the bearing.
- When low temperature reaction, the valve maybe frost, need to thaw before discharge.
- Serious stain glass pieces available dilute sulfuric acid cleaning.
- Checking the degree of wear of the sealing ring (corrosion), and replacement of wearing part in time, to ensure the vacuum degree of the equipment.
- Cleaning PTFE discharge valve frequently to avoid blinding and pollution to the material.
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